Skip Navigation

This Article
Right arrow Print PDF (3008K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (91)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Fuhrman, S. A.
Right arrow Articles by Peter Geiduschek, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fuhrman, S. A.
Right arrow Articles by Peter Geiduschek, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1981, Vol. 9, No. 23 6439-6456
© 1981

MOLECULAR BIOLOGY

Analysis of transcription of the human Alu family ubiquitous repeating element by eukaryotic RNA polymerase III

Shella A. Fuhrman*, Prescott L. Deininger+,{dagger}, Patricia LaPorte+, Theodore Friedmann+ and E. Peter Geiduschek*

*Department of Biology, University of California San Diego, La Jolla, CA 92093, USA +Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA

Received September 14, 1981.

A series of clones that contain human Alu family elements are actively transcribed in soluble in vitro RNA polymerase III systems. The 5' ends of the in vitro transcripts are located about 170 nucleotides upstream of the eponymous Alu I site of the repeat, while a region associated with specifying of the initiation site for in vitro transcription lies in the region between 79 and 106 nucleotides upstream of the central Alu site. Thus, the RNA polymerase III transcription unit defined by the human Alu family is similar to other RNA polymerase III transcription units in possessing an internal region that is required for active transcription in vitro.

{dagger}Present address of P.L.D.: Department of Biochrmistry, Louisiana State University Medical Center, New Orleans, LA 70112


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
N. Gal-Mark, S. Schwartz, and G. Ast
Alternative splicing of Alu exons--two arms are better than one
Nucleic Acids Res., April 1, 2008; 36(6): 2012 - 2023.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
N. Zingler, U. Willhoeft, H.-P. Brose, V. Schoder, T. Jahns, K.-M. O. Hanschmann, T. A. Morrish, J. Lower, and G. G. Schumann
Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joining
Genome Res., June 1, 2005; 15(6): 780 - 789.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
A. N. Carnell and J. I. Goodman
The Long (LINEs) and the Short (SINEs) of It: Altered Methylation as a Precursor to Toxicity
Toxicol. Sci., October 1, 2003; 75(2): 229 - 235.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
C. Aleman, A. M. Roy-Engel, T. H. Shaikh, and P. L. Deininger
Cis-acting influences on Alu RNA levels
Nucleic Acids Res., December 1, 2000; 28(23): 4755 - 4761.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. W. Englander and B. H. Howard
A Naturally Occurring T(14)A[IMAGE] Tract Blocks Nucleosome Formation Over the Human Neurofibromatosis Type 1 (NF1)-Alu Element
J. Biol. Chem., March 8, 1996; 271(10): 5819 - 5823.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. W. Englander and B. H. Howard
Nucleosome Positioning by Human Alu Elements in Chromatin
J. Biol. Chem., April 28, 1995; 270(17): 10091 - 10096.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.