Skip Navigation

This Article
Right arrow Print PDF (1029K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (296)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Yanofsky, C.
Right arrow Articles by Wu, A.M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yanofsky, C.
Right arrow Articles by Wu, A.M.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1981, Vol. 9, No. 24 6647-6668
© 1981


SURVEYS AND SUMMARIES

The complete nucleotide sequence of the tryptophan operon of Escherichia coli

C. Yanofsky1, T. Platt2, I.P. Crawford3, B.P. Nichols1, G.E. Christie2, H. Horowitz2, M. VanCleemput1 and A.M. Wu2

1Department of Biological Sciences, Stanford University Stanford, CA 94305 2Department of Molecular Biophysics and Biochemistry, Yale University New Haven, CT 06510 3Department of Microbiology, University of Iowa Iowa City, IA 52242, USA

Received November 11, 1981. The tryptophan (trp) operon of Escherichia coli has become the basic reference structure for studies on tryptophan metabolism. Within the past five years the application of recombinant DNA and sequencing methodologies has permitted the characterization of the structural and functional elements in this gene cluster at the molecular level. In this summary report we present the complete nucleotide sequence for the five structural genes of the trp operon of E. coli together with the internal and flanking regions of regulatory information.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
Nucleic Acids ResHome page
N. Bandmann and P.-A. Nygren
Combinatorial expression vector engineering for tuning of recombinant protein production in Escherichia coli
Nucleic Acids Res., March 12, 2007; 35(5): e32 - e32.
[Abstract] [Full Text] [PDF]


Home page
J. Bacteriol.Home page
H. Li and D. J. O'Sullivan
Identification of a nisI Promoter within the nisABCTIP Operon That May Enable Establishment of Nisin Immunity Prior to Induction of the Operon via Signal Transduction
J. Bacteriol., December 15, 2006; 188(24): 8496 - 8503.
[Abstract] [Full Text] [PDF]


Home page
J. Bacteriol.Home page
J. Loconto, P. Viswanathan, S. J. Nowak, M. Gloudemans, and L. Kroos
Identification of the {Omega}4406 Regulatory Region, a Developmental Promoter of Myxococcus xanthus, and a DNA Segment Responsible for Chromosomal Position-Dependent Inhibition of Gene Expression
J. Bacteriol., June 15, 2005; 187(12): 4149 - 4162.
[Abstract] [Full Text] [PDF]


Home page
J BiochemHome page
S. Kimura, T. Umemura, and T. Iyanagi
Two-Cistronic Expression Plasmids for High-Level Gene Expression in Escherichia coli Preventing Translational Initiation Inhibition Caused by the Intramolecular Local Secondary Structure of mRNA
J. Biochem., April 1, 2005; 137(4): 523 - 533.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. Yanofsky
Using Studies on Tryptophan Metabolism to Answer Basic Biological Questions
J. Biol. Chem., March 21, 2003; 278(13): 10859 - 10878.
[Full Text] [PDF]


Home page
MutagenesisHome page
T. Ohta, S.-i. Tokishita, R. Tsunoi, S. Ohmae, and H. Yamagata
Characterization of Trp+reversions in Escherichia coli strain WP2uvrA
Mutagenesis, July 1, 2002; 17(4): 313 - 316.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Hettwer and R. Sterner
A Novel Tryptophan Synthase beta -Subunit from the Hyperthermophile Thermotoga maritima. QUATERNARY STRUCTURE, STEADY-STATE KINETICS, AND PUTATIVE PHYSIOLOGICAL ROLE
J. Biol. Chem., March 1, 2002; 277(10): 8194 - 8201.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
M. Kaebernick, E. Dittmann, T. Borner, and B. A. Neilan
Multiple Alternate Transcripts Direct the Biosynthesis of Microcystin, a Cyanobacterial
Appl. Envir. Microbiol., February 1, 2002; 68(2): 449 - 455.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
J. Loh and G. Stacey
Nodulation Gene Regulation in Bradyrhizobium japonicum: a Unique Integration of Global Regulatory Circuits
Appl. Envir. Microbiol., January 1, 2002; 69(1): 10 - 17.
[Full Text] [PDF]


Home page
Cancer Res.Home page
W. Szeto, W. Jiang, D. A. Tice, B. Rubinfeld, P. G. Hollingshead, S. E. Fong, D. L. Dugger, T. Pham, D. G. Yansura, T. A. Wong, et al.
Overexpression of the Retinoic Acid-responsive Gene Stra6 in Human Cancers and Its Synergistic Induction by Wnt-1 and Retinoic Acid
Cancer Res., May 1, 2001; 61(10): 4197 - 4205.
[Abstract] [Full Text]


Home page
Proc. Natl. Acad. Sci. USAHome page
A. B. Khodursky, B. J. Peter, N. R. Cozzarelli, D. Botstein, P. O. Brown, and C. Yanofsky
DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli
PNAS, October 4, 2000; (2000) 220414297.
[Abstract] [Full Text]


Home page
J. Biol. Chem.Home page
P. Rondard and H. Bedouelle
A Mutational Approach Shows Similar Mechanisms of Recognition for the Isolated and Integrated Versions of a Protein Epitope
J. Biol. Chem., December 25, 1998; 273(52): 34753 - 34759.
[Abstract] [Full Text] [PDF]


Home page
J. Bacteriol.Home page
S.-T. Liang, P. P. Dennis, and H. Bremer
Expression of lacZ from the Promoter of the Escherichia coli spc Operon Cloned into Vectors Carrying the W205 trp-lac Fusion
J. Bacteriol., December 1, 1998; 180(23): 6090 - 6100.
[Abstract] [Full Text]


Home page
Microbiol. Mol. Biol. Rev.Home page
M. K. B. Berlyn
Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map
Microbiol. Mol. Biol. Rev., September 1, 1998; 62(3): 814 - 984.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Schwarz, K. Uthoff, C. Klinger, H. E. Meyer, P. Bartholmes, and M. Kaufmann
Multifunctional Tryptophan-synthesizing Enzyme. THE MOLECULAR WEIGHT OF THE EUGLENA GRACILIS PROTEIN IS UNEXPECTEDLY LOW
J. Biol. Chem., April 18, 1997; 272(16): 10616 - 10623.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
R Milkman and I. Crawford
Clustered third-base substitutions among wild strains of Escherichia coli
Science, July 22, 1983; 221(4608): 378 - 380.
[Abstract] [PDF]


Home page
ScienceHome page
E Yelverton, S Norton, J. Obijeski, and D. Goeddel
Rabies virus glycoprotein analogs: biosynthesis in Escherichia coli
Science, February 11, 1983; 219(4585): 614 - 620.
[Abstract] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
A. B. Khodursky, B. J. Peter, N. R. Cozzarelli, D. Botstein, P. O. Brown, and C. Yanofsky
DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli
PNAS, October 24, 2000; 97(22): 12170 - 12175.
[Abstract] [Full Text] [PDF]



Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.