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Nucleic Acids Research, 1981, Vol. 9, No. 8 1933-1939
© 1981

CHEMISTRY

5-(Carboxymethylaminomethyl)-2-thiouridine, a new modified nucleoside found at the first letter position of the anticodon

Yuko Yamada, Katsutoshi Murao and Hisayuki Ishikura

Received March 11, 1981. The structure of a modified uridine derivative which was detected at the first letter position of the anticodon of Bacillus subtilis tRNALys was determined to be 5-(carboxymethylaminomethyl)-2-thiouridine. The determination was mainly based in its ultraviolet absorption spectra and mass spectrometric analysis of the trimethylsilyl derivative.


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