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Nucleic Acids Research Advance Access published online on December 6, 2006
Nucleic Acids Research, doi:10.1093/nar/gkl1012
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© 2006 The Author(s).
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

Hedgehog Signaling Pathway Database: a repository of current annotation efforts and resources for the Hh research community

Kieran Hervold, Andrew Martin, Roger A. Kirkpatrick, Paul F. Mc Kenna* and F. A. Ramirez-Weber

Department of biology, Cell and Biology Group and Center for Computing in Life Sciences, San Francisco State University 1600 Holloway Avenue, 738 Hensill Hall, San Francisco CA 94132, USA

*To whom correspondence should be addressed. Tel/Fax: +1 415 740 8249; Email: paulmc{at}sfsu.edu

Received August 15, 2006. Revised October 31, 2006. Accepted November 1, 2006.

The Hedgehog Signaling Pathway Database is a curated repository of information pertaining to the Hedgehog developmental pathway. It was designed to provide centralized access to a wide range of relevant information in an organism-agnostic manner. Data are provided for all genes and gene targets known to be involved in the Hh pathway across various organisms. The data provided include DNA and protein sequences as well as domain structure motifs. All known human diseases associated with the Hh pathway are indexed including experimental data on therapeutic agents and their molecular targets. Hh researchers will find useful information on relevant protocols, tissue cell lines and reagents used in current Hh research projects. Curated content is also provided for publications, grants and patents relating to the Hh pathway. The database can be accessed at http://www.hedgehog.sfsu.edu.


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