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Nucleic Acids Research Advance Access published online on November 7, 2006
Nucleic Acids Research, doi:10.1093/nar/gkl808
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© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

PigGIS: Pig Genomic Informatics System

Jue Ruan1,2, Yiran Guo1,2, Heng Li1, Yafeng Hu1, Fei Song1, Xin Huang1, Karsten Kristiensen3, Lars Bolund1,4,* and Jun Wang1,3,4,*

1 Beijing Institute of Genomics of the Chinese Academy of Sciences, Beijing Genomics Institute Beijing 101300, China 2 Graduate University of the Chinese Academy of Sciences, Yuquan Road 19A Beijing 100039, China 3 Department of Biochemistry and Molecular Biology, University of Southern Denmark DK-5230 Odense M, Denmark 4 Institute of Human Genetics, University of Aarhus DK-8000 Aarhus C, Denmark

*To whom correspondence should be addressed. Tel: +86 10 80481552; Fax: +86 10 80498676; Email: wangj{at}genomics.org.cn

Received August 14, 2006. Revised September 21, 2006. Accepted September 29, 2006.

Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and position single nucleotide polymorphisms (SNPs) in different pig populations. It utilizes a variety of sequence data, including whole genome shotgun (WGS) reads and expressed sequence tags (ESTs), and achieves a successful mapping solution to the low-coverage genome problem. With the data presently available, we have identified a total of 15 700 pig consensus sequences covering 18.5 Mb of the homologous human exons. We have also recovered 18 700 SNPs and 20 800 unique 60mer oligonucleotide probes for future pig genome analyses. PigGIS can be freely accessed via the web at http://www.piggis.org/ and http://pig.genomics.org.cn/.

*Correspondence may also be addressed to Lars Bolund. Tel: +45 89421675; Fax: +45 86123173; Email: bolund{at}humgen.au.dk

The authors wish it to be known that, in their opinion, the first three authors should be regarded as joint First Authors


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