Nucleic Acids Research Advance Access published online on May 21, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm320
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Web Server Issue |
DSHIFT: a web server for predicting DNA chemical shifts
Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
*To whom correspondence should be addressed. Tel: +852 2609 8126; Fax: +852 2603 5057; Email: lams{at}cuhk.edu.hk
Received January 27, 2007. Revised March 31, 2007. Accepted April 17, 2007.
DSHIFT is a web server for predicting chemical shifts of DNA sequences in random coil form or double helical B-form. The prediction methods are based on sets of published reference chemical shift values and correction factors which account for shielding or deshielding effects from neighboring nucleotides. Proton, carbon and phosphorus chemical shift predictions are available for random coil DNAs. For double helical B-DNA, only proton chemical shift prediction is available. Results from these predictions will be useful for facilitating NMR resonance assignments and investigating structural features of solution DNA molecules. The URL of this server is: http://www.chem.cuhk.edu.hk/DSHIFT.