Nucleic Acids Research Advance Access published online on June 6, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm390
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DOMAC: an accurate, hybrid protein domain prediction server
School of Electrical Engineering and Computer Science, University of Central Florida, Orlando, FL, 32816, USA
*To whom correspondence should be addressed. Tel: (407) 823-0230; Fax: (407) 823-5419; Email: jcheng{at}cs.ucf.edu
Received January 12, 2007. Revised March 28, 2007. Accepted May 1, 2007.
Protein domain prediction is important for protein structure prediction, structure determination, function annotation, mutagenesis analysis and protein engineering. Here we describe an accurate protein domain prediction server (DOMAC) combining both template-based and ab initio methods. The preliminary version of the server was ranked among the top domain prediction servers in the seventh edition of Critical Assessment of Techniques for Protein Structure Prediction (CASP7), 2006. DOMAC server and datasets are available at: http://www.bioinfotool.org/domac.html