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Nucleic Acids Research Advance Access published online on December 26, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm873
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© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

The cell cycle DB: a systems biology approach to cell cycle analysis

Roberta Alfieri1,2,*, Ivan Merelli1, Ettore Mosca1 and Luciano Milanesi1

1Istituto di Tecnologie Biomediche—Consiglio Nazionale delle Ricerche, via F.lli Cervi 93, Segrate, Milano, Italy and 2CILEA, Consorzio Intrauniversitario per l’Elaborazione Automatica, via R. Sanzio 4, Segrate, Milano, Italy

*To whom correspondence should be addressed. Tel: +22 642 2600; Fax: +22 642 2600; Email: roberta.alfieri{at}itb.cnr.it

Received August 2, 2007. Revised September 30, 2007. Accepted October 1, 2007.

The cell cycle database is a biological resource that collects the most relevant information related to genes and proteins involved in human and yeast cell cycle processes. The database, which is accessible at the web site http://www.itb.cnr.it/cellcycle, has been developed in a systems biology context, since it also stores the cell cycle mathematical models published in the recent years, with the possibility to simulate them directly. The aim of our resource is to give an exhaustive view of the cell cycle process starting from its building-blocks, genes and proteins, toward the pathway they create, represented by the models.


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