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Nucleic Acids Research Advance Access published online on November 3, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm925
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© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

IDBD: Infectious Disease Biomarker Database

In Seok Yang1, Chunsun Ryu2, Ki Joon Cho1, Jin Kwang Kim1, Swee Hoe Ong3, Wayne P. Mitchell4,5, Bong Su Kim2, Hee-Bok Oh2 and Kyung Hyun Kim6,*

1Department of Life Sciences & Biotechnology, School of Life Sciences & Biotechnology, Korea University, Seoul, Korea, 2Center for Infectious Diseases, Korea National Institute of Health, Seoul, Korea, 3Genome Institute of Singapore, A*STAR, 60 Biopolis Street, Singapore, 4Experimental Therapeutics Center, 31 Biopolis Street, Singapore, 5Division of Information Systems, School of Computer Engineering, Nanyang Technological University, Singapore and 6Department of Biotechnology & Bioinformatics, College of Science & Technology, Korea University, Chungnam, Korea

*To whom correspondence should be addressed. Tel: 82-2-3290-3444; Fax: 82-2-3290-3945; Email: khkim{at}korea.ac.kr Correspondence may also be addressed to Hee-Bok Oh. Tel: 82-2-355-5601; Fax: 82-2-382-4891; Email: hboh{at}nih.go.kr

Received August 14, 2007. Revised September 14, 2007. Accepted October 10, 2007.

Biomarkers enable early diagnosis, guide molecularly targeted therapy and monitor the activity and therapeutic responses across a variety of diseases. Despite intensified interest and research, however, the overall rate of development of novel biomarkers has been falling. Moreover, no solution is yet available that efficiently retrieves and processes biomarker information pertaining to infectious diseases. Infectious Disease Biomarker Database (IDBD) is one of the first efforts to build an easily accessible and comprehensive literature-derived database covering known infectious disease biomarkers. IDBD is a community annotation database, utilizing collaborative Web 2.0 features, providing a convenient user interface to input and revise data online. It allows users to link infectious diseases or pathogens to protein, gene or carbohydrate biomarkers through the use of search tools. It supports various types of data searches and application tools to analyze sequence and structure features of potential and validated biomarkers. Currently, IDBD integrates 611 biomarkers for 66 infectious diseases and 70 pathogens. It is publicly accessible at http://biomarker.cdc.go.kr and http://biomarker.korea.ac.kr.


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