Nucleic Acids Research Advance Access published online on November 8, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm975
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WormBase 2007
1Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK, 2Division of Biology 156-29, Pasadena, CA 91125, 3Genome Sequencing Center, Washington University School of Medicine St Louis, MO 63108, 4Cold Spring Harbor Laboratory, 1 Bungtown Road Cold Spring Harbor, NY 11724 and 5Howard Hughes Medical Institute, California Institute of Technology Pasadena, CA 91125, USA
*To whom correspondence should be addressed. Tel: +1223 496892; Fax: +1223 496802; Email: ar2{at}sanger.ac.uk
Received September 13, 2007. Revised October 18, 2007. Accepted October 18, 2007.
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence information, WormBase now includes the genomic, anatomical and functional information about C. elegans, other Caenorhabditis species and other nematodes. As such, it is a crucial resource not only for C. elegans biologists but the larger biomedical and bioinformatics communities. Coverage of core areas of C. elegans biology will allow the biomedical community to make full use of the results of intensive molecular genetic analysis and functional genomic studies of this organism. Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences.
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