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Nucleic Acids Research Advance Access published online on November 13, 2007
Nucleic Acids Research, doi:10.1093/nar/gkm988
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© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

Ensembl 2008

P. Flicek1,*, B. L. Aken2, K. Beal1, B. Ballester1, M. Caccamo1, Y. Chen1, L. Clarke2, G. Coates2, F. Cunningham2, T. Cutts2, T. Down2, S. C. Dyer2, T. Eyre2, S. Fitzgerald1, J. Fernandez-Banet2, S. Gräf1, S. Haider1, M. Hammond1, R. Holland1, K. L. Howe2, K. Howe2, N. Johnson1, A. Jenkinson1, A. Kähäri1, D. Keefe1, F. Kokocinski2, E. Kulesha1, D. Lawson1, I. Longden1, K. Megy1, P. Meidl1, B. Overduin1, A. Parker2, B. Pritchard2, A. Prlic2, S. Rice2, D. Rios1, M. Schuster1, I. Sealy2, G. Slater1, D. Smedley1, G. Spudich1, S. Trevanion2, A. J. Vilella1, J. Vogel2, S. White2, M. Wood2, E. Birney1, T. Cox2, V. Curwen2, R. Durbin2, X. M. Fernandez-Suarez1, J. Herrero1, T. J. P. Hubbard2, A. Kasprzyk1, G. Proctor1, J. Smith2, A. Ureta-Vidal1 and S. Searle2

1European Bioinformatics Institute (EMBL-EBI) and 2Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK

*To whom correspondence should be addressed. Tel: + 44 1223 492581; Fax: +44 1223 494468; Email: flicek{at}ebi.ac.uk

Received September 15, 2007. Revised October 18, 2007. Accepted October 19, 2007.

The Ensembl project (http://www.ensembl.org) is a comprehensive genome information system featuring an integrated set of genome annotation, databases and other information for chordate and selected model organism and disease vector genomes. As of release 47 (October 2007), Ensembl fully supports 35 species, with preliminary support for six additional species. New species in the past year include platypus and horse. Major additions and improvements to Ensembl since our previous report include extensive support for functional genomics data in the form of a specialized functional genomics database, genome-wide maps of protein–DNA interactions and the Ensembl regulatory build; support for customization of the Ensembl web interface through the addition of user accounts and user groups; and increased support for genome resequencing. We have also introduced new comparative genomics-based data mining options and report on the continued development of our software infrastructure.


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