Nucleic Acids Research Advance Access published online on September 19, 2008
Nucleic Acids Research, doi:10.1093/nar/gkn597
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DiProDB: a database for dinucleotide properties
1Biocomputing Group, Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, 2Department of Bioinformatics, Friedrich-Schiller-University Jena, Ernst-Abbe-Platz 2, 07743 Jena, Germany and 3Theoretical Systems Biology, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
*To whom correspondence should be addressed. Tel: +44 1603 255313; Fax: +44 1603 255128; Email: thomas.wilhelm{at}bbsrc.ac.uk
Received August 1, 2008. Revised September 3, 2008. Accepted September 3, 2008.
DiProDB (http://diprodb.fli-leibniz.de) is a database of conformational and thermodynamic dinucleotide properties. It includes datasets both for DNA and RNA, as well as for single and double strands. The data have been shown to be important for understanding different aspects of nucleic acid structure and function, and they can also be used for encoding nucleic acid sequences. The database is intended to facilitate further applications of dinucleotide properties. A number of property datasets is highly correlated. Therefore, the database comes with a correlation analysis facility. Authors having determined new sets of dinucleotide property values are invited to submit these data to DiProDB.
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