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Nucleic Acids Research Advance Access published online on October 23, 2008
Nucleic Acids Research, doi:10.1093/nar/gkn784
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© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

OperonDB: a comprehensive database of predicted operons in microbial genomes

Mihaela Pertea*, Kunmi Ayanbule, Megan Smedinghoff and Steven L. Salzberg

Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA

*To whom correspondence should be addressed. Tel: +1 301 405 9762; Fax: +1 301 314 1341; Email: mpertea{at}umiacs.umd.edu

Received September 11, 2008. Revised October 8, 2008. Accepted October 9, 2008.

The fast pace of bacterial genome sequencing and the resulting dependence on highly automated annotation methods has driven the development of many genome-wide analysis tools. OperonDB, first released in 2001, is a database containing the results of a computational algorithm for locating operon structures in microbial genomes. OperonDB has grown from 34 genomes in its initial release to more than 500 genomes today. In addition to increasing the size of the database, we have re-designed our operon finding algorithm and improved its accuracy. The new database is updated regularly as additional genomes become available in public archives. OperonDB can be accessed at: http://operondb.cbcb.umd.edu


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