Skip Navigation



Nucleic Acids Research Advance Access published online on November 4, 2008
Nucleic Acids Research, doi:10.1093/nar/gkn799
This Article
Right arrow Full Text Freely available
Right arrow Print PDF (2726K) Freely available
Right arrow Screen PDF (297K) Freely available
Right arrowOA All Versions of this Article:
37/suppl_1/D647    most recent
gkn799v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Driscoll, T.
Right arrow Articles by Sobral, B. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Driscoll, T.
Right arrow Articles by Sobral, B. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

PIG—the pathogen interaction gateway

Tim Driscoll1, Matthew D. Dyer1, T. M. Murali2 and Bruno W. Sobral1,*

1Virginia Bioinformatics Institute and 2Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA

*To whom correspondence should be addressed. Tel: +1 540 231 2582; Fax: +1 540 231 2606; Email: sobral{at}vt.edu

Correspondence may also be addressed to T. M. Murali. Tel: +1 540 231 8534; Fax: +1 540 231 6075; Email: murali{at}cs.vt.edu

Received August 15, 2008. Revised September 15, 2008. Accepted October 10, 2008.

Protein–protein interactions (PPIs) play a vital role in initiating infection in a number of pathogens. Identifying which interactions allow a pathogen to infect its host can help us to understand methods of pathogenesis and provide potential targets for therapeutics. Public resources for studying host–pathogen systems, in particular PPIs, are scarce. To facilitate the study of host–pathogen PPIs, we have collected and integrated host–pathogen PPI (HP–PPI) data from a number of public resources to create the Pathogen Interaction Gateway (PIG). PIG provides a text based search and a BLAST interface for searching the HP–PPI data. Each entry in PIG includes information such as the functional annotations and the domains present in the interacting proteins. PIG provides links to external databases to allow for easy navigation among the various websites. Additionally, PIG includes a tool for visualizing a single HP–PPI network or two HP–PPI networks. PIG can be accessed at http://pig.vbi.vt.edu.

Present address: Matthew D. Dyer, Department of Microbiology, University of Washington, Seattle, WA 98195, USA


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.