Nucleic Acids Research

Editorial:

Editorial
Nucl. Acids Res. 2000 28: 0; doi:10.1093/nar/28.21.0 [Print PDF] [Request Permissions]  

Survey and Summary:

Aidan J. Doherty and Se Won Suh

Structural and mechanistic conservation in DNA ligases
Nucl. Acids Res. 2000 28: 4051-4058; doi:10.1093/nar/28.21.4051 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Articles:

Birgit Bramlage, Ettore Luzi, and Fritz Eckstein

HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell culture
Nucl. Acids Res. 2000 28: 4059-4067; doi:10.1093/nar/28.21.4059 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Andrew M. Borman, Yanne M. Michel, and Katherine M. Kean

Biochemical characterisation of cap–poly(A) synergy in rabbit reticulocyte lysates: the eIF4G–PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5'-end
Nucl. Acids Res. 2000 28: 4068-4075; doi:10.1093/nar/28.21.4068 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Staci Nole-Wilson and Beth A. Krizek

DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA
Nucl. Acids Res. 2000 28: 4076-4082; doi:10.1093/nar/28.21.4076 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Bernhard Suter, Georg Schnappauf, and Fritz Thoma

Poly(dA·dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo
Nucl. Acids Res. 2000 28: 4083-4089; doi:10.1093/nar/28.21.4083 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Marco Musso, Giovanna Bianchi-Scarrà, and Michael W. Van Dyke

The yeast CDP1 gene encodes a triple-helical DNA-binding protein
Nucl. Acids Res. 2000 28: 4090-4096; doi:10.1093/nar/28.21.4090 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

You-Di Liao, Huey-Chung Huang, Yin-Jen Leu, Chyou-Wei Wei, Pin-Chi Tang, and Sui-Chi Wang

Purification and cloning of cytotoxic ribonucleases from Rana catesbeiana (bullfrog)
Nucl. Acids Res. 2000 28: 4097-4104; doi:10.1093/nar/28.21.4097 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Jill A. Gershan and Kathleen M. Karrer

A family of developmentally excised DNA elements in Tetrahymena is under selective pressure to maintain an open reading frame encoding an integrase-like protein
Nucl. Acids Res. 2000 28: 4105-4112; doi:10.1093/nar/28.21.4105 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Mohammed Amarzguioui, Gaute Brede, Eshrat Babaie, Morten Grøtli, Brian Sproat, and Hans Prydz

Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes
Nucl. Acids Res. 2000 28: 4113-4124; doi:10.1093/nar/28.21.4113 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Siddhesh D. Patil and David G. Rhodes

Conformation of oligodeoxynucleotides associated with anionic liposomes
Nucl. Acids Res. 2000 28: 4125-4129; doi:10.1093/nar/28.21.4125 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Nancy Beerens, Fedde Groot, and Ben Berkhout

Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription
Nucl. Acids Res. 2000 28: 4130-4137; doi:10.1093/nar/28.21.4130 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Yanbin Zhang, Fenghua Yuan, Xiaohua Wu, Mu Wang, Olga Rechkoblit, John-Stephen Taylor, Nicholas E. Geacintov, and Zhigang Wang

Error-free and error-prone lesion bypass by human DNA polymerase in vitro
Nucl. Acids Res. 2000 28: 4138-4146; doi:10.1093/nar/28.21.4138 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Yanbin Zhang, Fenghua Yuan, Hua Xin, Xiaohua Wu, Deepak K. Rajpal, Danzhou Yang, and Zhigang Wang

Human DNA polymerase synthesizes DNA with extraordinarily low fidelity
Nucl. Acids Res. 2000 28: 4147-4156; doi:10.1093/nar/28.21.4147 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Bing Zhu, Yong Zheng, Herbert Angliker, Steffen Schwarz, Stéphane Thiry, Michel Siegmann, and Jean-Pierre Jost

5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence
Nucl. Acids Res. 2000 28: 4157-4165; doi:10.1093/nar/28.21.4157 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Ralf Emmerich, Philipp Strehler, Hauke Hennecke, and Hans-Martin Fischer

An imperfect inverted repeat is critical for DNA binding of the response regulator RegR of Bradyrhizobium japonicum
Nucl. Acids Res. 2000 28: 4166-4171; doi:10.1093/nar/28.21.4166 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Timur M. Yusufzai and Alan P. Wolffe

Functional consequences of Rett syndrome mutations on human MeCP2
Nucl. Acids Res. 2000 28: 4172-4179; doi:10.1093/nar/28.21.4172 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Wei Liu and Stuart Linn

Proteolysis of the human DNA polymerase catalytic subunit by caspase-3 and calpain specifically during apoptosis
Nucl. Acids Res. 2000 28: 4180-4188; doi:10.1093/nar/28.21.4180 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Rubén D. Flores-Saaib and Albert J. Courey

Analysis of Groucho–histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression
Nucl. Acids Res. 2000 28: 4189-4196; doi:10.1093/nar/28.21.4189 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Tai-Chih Kuo and David L. Herrin

Quantitative studies of Mn²⁺-promoted specific and non-specific cleavages of a large RNA: Mn²⁺-GAAA ribozymes and the evolution of small ribozymes
Nucl. Acids Res. 2000 28: 4197-4206; doi:10.1093/nar/28.21.4197 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Ernst G. Malygin, William M. Lindstrom, Jr, Samuel L. Schlagman, Stanley Hattman, and Norbert O. Reich

Pre-steady state kinetics of bacteriophage T4 Dam DNA-[N⁶-adenine] methyltransferase: interaction with native (GATC) or modified sites
Nucl. Acids Res. 2000 28: 4207-4211; doi:10.1093/nar/28.21.4207 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Masahiko Nitta, Masafumi Saijo, Naohiko Kodo, Toshiro Matsuda, Yoshimichi Nakatsu, Hiroshi Tamai, and Kiyoji Tanaka

A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA
Nucl. Acids Res. 2000 28: 4212-4218; doi:10.1093/nar/28.21.4212 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Sven A. Koenig Merediz, Manuel Schmidt, Georg J. Hoppe, Jens Alfken, David Meraro, Ben-Zion Levi, Andreas Neubauer, and Burghardt Wittig

Cloning of an interferon regulatory factor 2 isoform with different regulatory ability
Nucl. Acids Res. 2000 28: 4219-4224; doi:10.1093/nar/28.21.4219 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Hoon Yoo and R. L. Juliano

Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers
Nucl. Acids Res. 2000 28: 4225-4231; doi:10.1093/nar/28.21.4225 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Takako Takanami, Akiyuki Mori, Hideyuki Takahashi, and Atsushi Higashitani

Hyper-resistance of meiotic cells to radiation due to a strong expression of a single recA-like gene in Caenorhabditis elegans
Nucl. Acids Res. 2000 28: 4232-4236; doi:10.1093/nar/28.21.4232 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Judith N. Burstyn, Wendy J. Heiger-Bernays, Seth M. Cohen, and Stephen J. Lippard

Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent
Nucl. Acids Res. 2000 28: 4237-4243; doi:10.1093/nar/28.21.4237 [Abstract] [FREE Full Text] [Print PDF] [Supplementary Data] [Request Permissions]  

Adrienne Adams, J. Mitchell Guss, Charles A. Collyer, William A. Denny, and Laurence P. G. Wakelin

A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)₂
Nucl. Acids Res. 2000 28: 4244-4253; doi:10.1093/nar/28.21.4244 [Abstract] [FREE Full Text] [Print PDF] [Supplementary Data] [Request Permissions]  

Andriy A. Mokhir and Clemens Richert

Synthesis and monitored selection of 5'-nucleobase-capped oligodeoxyribonucleotides
Nucl. Acids Res. 2000 28: 4254-4265; doi:10.1093/nar/28.21.4254 [Abstract] [FREE Full Text] [Print PDF] [Supplementary Data] [Request Permissions]  

Xiukun Lin, Nobuyuki Mizunuma, Tian-men Chen, Sitki M. Copur, Gladys F. Maley, Jun Liu, Frank Maley, and Edward Chu

In vitro selection of an RNA sequence that interacts with high affinity with thymidylate synthase
Nucl. Acids Res. 2000 28: 4266-4274; doi:10.1093/nar/28.21.4266 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Frank Hartung, Helena Plchová, and Holger Puchta

Molecular characterisation of RecQ homologues in Arabidopsis thaliana
Nucl. Acids Res. 2000 28: 4275-4282; doi:10.1093/nar/28.21.4275 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Zsofia Intody, Brian D. Perkins, John H. Wilson, and Theodore G. Wensel

Blocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinking
Nucl. Acids Res. 2000 28: 4283-4290; doi:10.1093/nar/28.21.4283 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Susumu Itoh, Johan Ericsson, Jun-ichi Nishikawa, Carl-Henrik Heldin, and Peter ten Dijke

The transcriptional co-activator P/CAF potentiates TGF-ß/Smad signaling
Nucl. Acids Res. 2000 28: 4291-4298; doi:10.1093/nar/28.21.4291 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Finn Werner, Jyrki J. Eloranta, and Robert O. J. Weinzierl

Archaeal RNA polymerase subunits F and P are bona fide homologs of eukaryotic RPB4 and RPB12
Nucl. Acids Res. 2000 28: 4299-4305; doi:10.1093/nar/28.21.4299 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Jeffrey N. Lindquist, Stefan G. Kauschke, Branko Stefanovic, Elmar R. Burchardt, and David A. Brenner

Characterization of the interaction between CP₂ and the 3'-untranslated region of collagen 1(I) mRNA
Nucl. Acids Res. 2000 28: 4306-4316; doi:10.1093/nar/28.21.4306 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Hideto Takami, Kaoru Nakasone, Yoshihiro Takaki, Go Maeno, Rumie Sasaki, Noriaki Masui, Fumie Fuji, Chie Hirama, Yuka Nakamura, Naotake Ogasawara, Satoru Kuhara, and Koki Horikoshi

Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis
Nucl. Acids Res. 2000 28: 4317-4331; doi:10.1093/nar/28.21.4317 [Abstract] [FREE Full Text] [Print PDF] [Supplementary Data] [Request Permissions]  

Howard B. Gamper, Hetal Parekh, Michael C. Rice, Michael Bruner, Heather Youkey, and Eric B. Kmiec

The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts
Nucl. Acids Res. 2000 28: 4332-4339; doi:10.1093/nar/28.21.4332 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Haiying Hang, Sarah J. Rauth, Kevin M. Hopkins, and Howard B. Lieberman

Mutant alleles of Schizosaccharomyces pombe rad9⁺ alter hydroxyurea resistance, radioresistance and checkpoint control
Nucl. Acids Res. 2000 28: 4340-4349; doi:10.1093/nar/28.21.4340 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

D. G. Murdock, N. C. Christacos, and D. C. Wallace

The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method
Nucl. Acids Res. 2000 28: 4350-4355; doi:10.1093/nar/28.21.4350 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Markus C. Wahl and Muttaiya Sundaralingam

B-form to A-form conversion by a 3'-terminal ribose: crystal structure of the chimera d(CCACTAGTG)r(G)
Nucl. Acids Res. 2000 28: 4356-4363; doi:10.1093/nar/28.21.4356 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

M. Burset, I. A. Seledtsov, and V. V. Solovyev

Analysis of canonical and non-canonical splice sites in mammalian genomes
Nucl. Acids Res. 2000 28: 4364-4375; doi:10.1093/nar/28.21.4364 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Junpeng Deng and Muttaiya Sundaralingam

Synthesis and crystal structure of an octamer RNA r(guguuuac)/r(guaggcac) with G·G/U·U tandem wobble base pairs: comparison with other tandem G·U pairs
Nucl. Acids Res. 2000 28: 4376-4381; doi:10.1093/nar/28.21.4376 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Martin Zofall and Blaine Bartholomew

Two novel dATP analogs for DNA photoaffinity labeling
Nucl. Acids Res. 2000 28: 4382-4390; doi:10.1093/nar/28.21.4382 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Isabelle Saves, Heïdy Eleaume, Jacques Dietrich, and Jean-Michel Masson

The Thy Pol-2 intein of Thermococcus hydrothermalis is an isoschizomer of PI-TliI and PI-TfuII endonucleases
Nucl. Acids Res. 2000 28: 4391-4396; doi:10.1093/nar/28.21.4391 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Francisco Martínez-Abarca and Nicolás Toro

RecA-independent ectopic transposition in vivo of a bacterial group II intron
Nucl. Acids Res. 2000 28: 4397-4402; doi:10.1093/nar/28.21.4397 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

NAR Methods Online:

Martin Holzenberger, Claudia Lenzner, Patricia Leneuve, Randa Zaoui, Ghislaine Hamard, Sophie Vaulont, and Yves Le Bouc

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene
Nucl. Acids Res. 2000 28: e92; doi:10.1093/nar/28.21.e92 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Timur Shtatland, Stanley C. Gill, Brenda E. Javornik, Hans E. Johansson, Britta S. Singer, Olke C. Uhlenbeck, Dominic A. Zichi, and Larry Gold

Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX
Nucl. Acids Res. 2000 28: e93; doi:10.1093/nar/28.21.e93 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

O. K. Kaboev, L. A. Luchkina, A. N. Tret’iakov, and A. R. Bahrmand

PCR hot start using primers with the structure of molecular beacons (hairpin-like structure)
Nucl. Acids Res. 2000 28: e94; doi:10.1093/nar/28.21.e94 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

Céline Fabret, Sandrine Poncet, Steffen Danielsen, Torben V. Borchert, S. Dusko Ehrlich, and Laurent Jannière

Efficient gene targeted random mutagenesis in genetically stable Escherichia coli strains
Nucl. Acids Res. 2000 28: e95; doi:10.1093/nar/28.21.e95 [Abstract] [FREE Full Text] [Print PDF] [Request Permissions]  

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