Cover. Schematic diagram of some commonly used methods for SNP detection. Genotyping methods are used to detect known SNPs and include ligase detection, Taqman, Molecular Beacons, the Invader assay and primer extension. Scanning methods such as Endo V/ligase are used to identify novel or low abundance SNPs. See the paper by Kirk et al. in this issue [Nucleic Acids Res. (2002) 30, 3295-3311].
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