Cover. Small Cajal body-specific RNAs (scaRNAs). Structural classification of a recently discovered class of 2′O-ribose-methylation and pseudouridylation guide RNAs which reside in the nucleoplasmic Cajal (coiled) body and direct modification of the RNA polymerase II-transcribed U1, U2, U4 and U5 spliceosomal snRNAs. The U93 scaRNA co-localises with p80 coilin, a molecular marker of the Cajal body. For further details see the paper by Kiss et al. in this issue [Nucleic Acids Res. (2002) 30, 4643--4649].
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