Cover. Overview of the Cre-loxP synaptic complex (left) represented with the solvent accessible surface (probe radius 1.4 
-phosphotyrosine covalent intermediate (bottom). Direct interactions between amino acids and DNA are represented with green lines. The scissile bond is depicted in yellow. For further details see the paper by Ennifar et al. in this issue [Nucleic Acids Res. 31, 5449--5460].
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