Cover. Schematic representation of the design of a P4-P6 RNA derivative containing a kink-turn RNA motif. Left, J5/5a hinge region (highlighted in yellow) of native P4-P6 RNA derived from the Tetrahymena group I intron was deleted; center, the kink-turn motif (in red) was inserted between two helical stem regions by replacing the J5/5a hinge; right, the completed P4-P6 derivative with the kink-turn motif. The RNA was designed by using a molecular modeling program, Insight II. For further information see the paper by Matsumura et al. in this issue [Nucleic Acids Res. 31, 5544--5551].
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