Cover.
Modification-dependent tRNA binding to cognate codon on the 30S ribosomal subunit at 3 Å resolution. The position 37 modified nucleoside N6-threnonylcarbamoyl (red) adenosine (yellow) acts as a platform for the anticodon stem and loop domain of human tRNALys3 (gray) to bind cognate codon (blue). Anticodon U34 (aqua), U35 (green) and U36 (tan) are bound to codon AAA (blue). [Murphy,F., Malkiewicz,A., Agris,P.F. and Ramakrishnan,V., unpublished]. For further details see the paper by Agris in this issue [Nucleic Acids Res. (2004) 32, 223-238].
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