Cover: Detecting seeded motifs in DNA sequences. DNA motifs of functional significance are often composed of regions showing different extent of variability. A motif searching web tool (MOST) was developed to extract overrepresented exact patterns from input sequences and to cluster them to produce motifs core regions, which are then extended and scored to generate seeded motifs {see article by Pizzi et al. in this issue [Nucleic Acids Res. (2005), 33, e135]}.
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