Cover: The structure of a 71 bp bent DNA model illustrating average counter-ion occupations at the phosphates calculated by Monte Carlo simulation using a linear-scaling Green's function solvation approach. Red indicates higher occupancy. The bent DNA model was based on the crystallographic structure of approximately one full turn of histone-bound DNA in a nucleosome core particle (PDB entry 1AOI). The calculations predict that phosphate-phosphate repulsions account for approximately 30% of the total free energy required to bend DNA from canonical linear B-form into the conformation found in the nucleosome core particle. For further details see the paper by Range et al. in this issue: Nucleic Acids Res. (2005), 33, 1257-1268.
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