Cover: 2007 marks the 30th anniversary of the development of the ‘dideoxy’ sequencing methods of Fred Sanger and his colleagues at the MRC Laboratory of Molecular Biology in Cambridge, UK that formed the basis for automated DNA sequencing technology and which led to the establishment of human and many other genome sequences. Although other methods were also invented (notably that of Maxam/Gilbert), Sanger's methods have stood the test of time and it is only in recent years that newer DNA sequencing techniques have started to emerge as contenders. A Survey and Summary on “DNA sequencing from bench to bedside” will be published in NAR in Spring 2007. Sanger's photo is copyright of the MRC Laboratory of Molecular Biology.
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