Cover: The STRING database (Search Tool for the Retrieval of Interacting Genes/Proteins) contains known and predicted protein interactions, integrated over a variety of data sources and prediction algorithms. The database centers on precomputed protein networks for hundreds of organisms, augmented with accessory data including alignments and protein domain architectures (lower left), detailed information on genomic context (lower right), and results from automated textmining. The main part of the cover image shows a subset of the protein network of yeast, from the STRING website, next to a microscopic image of mammalian cells (Vero cells stained for the microtubule cytoskeleton in red, the COPI coat complex of the Golgi in green, and the nucleus in blue; image credit: Jeremy Simpson, Cell Biology and Biophysics Unit, EMBL Heidelberg).
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