Cover: Structure of the region of the ribosome containing RNA bases encoded by the target site for the analogous homing endonucleases I-VdiI and I-PpoI. The bases corresponding to these enzymes' target (shown in red) include nucleotides involved in ribosome intersubunit contacts, tRNA contacts and binding of the ribosome recycling factor. Green and gold surfaces are 23S rRNA and 50S protein, respectively. Cyan and purple bases are P-site and A-site tRNA. Grey bases are additional nucleotides of the ribosome's 'H69' helix. The ribbon diagrams show I-VdiI (foreground) and I-PpoI (background) bound to their analogous rDNA targets. For further information, see the article by N. Nomura et al. in this issue (Nucleic Acids Res. 2008;
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