Nucleic Acids Research

Survey and Summary

Get checked abstract Yuri Motorin, Frank Lyko, and Mark Helm

5-methylcytosine in RNA: detection, enzymatic formation and biological functions
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: 1415-1430; doi:10.1093/nar/gkp1117 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Gene Regulation, Chromatin and Epigenetics

Get checked abstract Yakun Wan, Jung-Hsien Chiang, Chan-Hsien Lin, Christina E. Arens, Ramsey A. Saleem, Jennifer J. Smith, and John D. Aitchison

Histone chaperone Chz1p regulates H2B ubiquitination and subtelomeric anti-silencing
Nucleic Acids Research Advance Access published on December 14, 2009
Nucl. Acids Res. 2010 38: 1431-1440; doi:10.1093/nar/gkp1099 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract T. Y. Erkina, Y. Zou, S. Freeling, V. I. Vorobyev, and A. M. Erkine

Functional interplay between chromatin remodeling complexes RSC, SWI/SNF and ISWI in regulation of yeast heat shock genes
Nucleic Acids Research Advance Access published on December 16, 2009
Nucl. Acids Res. 2010 38: 1441-1449; doi:10.1093/nar/gkp1130 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Genome Integrity, Repair and Replication

Get checked abstract Ronita Nag, McKenna Kyriss, John W. Smerdon, John J. Wyrick, and Michael J. Smerdon

A cassette of N-terminal amino acids of histone H2B are required for efficient cell survival, DNA repair and Swi/Snf binding in UV irradiated yeast
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1450-1460; doi:10.1093/nar/gkp1074 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Shivani Malik, Priyasri Chaurasia, Shweta Lahudkar, Geetha Durairaj, Abhijit Shukla, and Sukesh R. Bhaumik

Rad26p, a transcription-coupled repair factor, is recruited to the site of DNA lesion in an elongating RNA polymerase II-dependent manner in vivo
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1461-1477; doi:10.1093/nar/gkp1147 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Pierre Boesch, Noha Ibrahim, André Dietrich, and Robert N. Lightowlers

Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria
Nucleic Acids Research Advance Access published on December 10, 2009
Nucl. Acids Res. 2010 38: 1478-1488; doi:10.1093/nar/gkp1143 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Olivier J. Becherel, Burkhard Jakob, Amy L. Cherry, Nuri Gueven, Markus Fusser, Amanda W. Kijas, Cheng Peng, Sachin Katyal, Peter J. McKinnon, Junjie Chen, Bernd Epe, Stephen J. Smerdon, Gisela Taucher-Scholz, and Martin F. Lavin

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response
Nucleic Acids Research Advance Access published on December 14, 2009
Nucl. Acids Res. 2010 38: 1489-1503; doi:10.1093/nar/gkp1149 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Genomics

Get checked abstract Jonathan Livny and Matthew K. Waldor

Mining regulatory 5'UTRs from cDNA deep sequencing datasets
Nucleic Acids Research Advance Access published on December 7, 2009
Nucl. Acids Res. 2010 38: 1504-1514; doi:10.1093/nar/gkp1121 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Asaf Levy, Schraga Schwartz, and Gil Ast

Large-scale discovery of insertion hotspots and preferential integration sites of human transposed elements
Nucleic Acids Research Advance Access published on December 14, 2009
Nucl. Acids Res. 2010 38: 1515-1530; doi:10.1093/nar/gkp1134 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Molecular Biology

Get checked abstract Jacques Bonnet, Marthe Colotte, Delphine Coudy, Vincent Couallier, Joseph Portier, Bénédicte Morin, and Sophie Tuffet

Chain and conformation stability of solid-state DNA: implications for room temperature storage
Nucleic Acids Research Advance Access published on December 7, 2009
Nucl. Acids Res. 2010 38: 1531-1546; doi:10.1093/nar/gkp1060 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Jie Yi, Na Chang, Xinwen Liu, Gaier Guo, Lixiang Xue, Tanjun Tong, Myriam Gorospe, and Wengong Wang

Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: 1547-1558; doi:10.1093/nar/gkp1114 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract J. Saadi Imam, Jayanthi P. Gudikote, Wai-kin Chan, and Miles F. Wilkinson

Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1559-1574; doi:10.1093/nar/gkp1115 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Samuel J. Balin and Marilia Cascalho

The rate of mutation of a single gene
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1575-1582; doi:10.1093/nar/gkp1119 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract Chul-Hwan Lee, Yong-Keol Shin, Thi Thu Huong Phung, Jae Seok Bae, Young-Hoon Kang, Tuan Anh Nguyen, Jeong-Hoon Kim, Do-Hyung Kim, Min-Jung Kang, Sung-Ho Bae, and Yeon-Soo Seo

Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1583-1595; doi:10.1093/nar/gkp1135 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract Woo-Ram Lee, Ji-Young Jang, Jeong-Sun Kim, Myung-Hee Kwon, and Yong-Sung Kim

Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1596-1609; doi:10.1093/nar/gkp1145 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Martin Lützelberger, Claudia A. Bottner, Wiebke Schwelnus, Susanne Zock-Emmenthal, Aleh Razanau, and Norbert F. Käufer

The N-terminus of Prp1 (Prp6/U5-102 K) is essential for spliceosome activation in vivo
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1610-1622; doi:10.1093/nar/gkp1155 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Enid W. Choi, Lalitha V. Nayak, and Paula J. Bates

Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides
Nucleic Acids Research Advance Access published on December 11, 2009
Nucl. Acids Res. 2010 38: 1623-1635; doi:10.1093/nar/gkp1088 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Katarzyna Potrykus, Helen Murphy, Xiongfong Chen, Jonathan A. Epstein, and Michael Cashel

Imprecise transcription termination within Escherichia coli greA leader gives rise to an array of short transcripts, GraL
Nucleic Acids Research Advance Access published on December 14, 2009
Nucl. Acids Res. 2010 38: 1636-1651; doi:10.1093/nar/gkp1150 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Nucleic Acid Enzymes

Get checked abstract Katarzyna H. Kaminska, Elzbieta Purta, Lykke H. Hansen, Janusz M. Bujnicki, Birte Vester, and Katherine S. Long

Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria
Nucleic Acids Research Advance Access published on December 10, 2009
Nucl. Acids Res. 2010 38: 1652-1663; doi:10.1093/nar/gkp1142 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Richard D. Hutton, Timothy D. Craggs, Malcolm F. White, and J.Carlos Penedo

PCNA and XPF cooperate to distort DNA substrates
Nucleic Acids Research Advance Access published on December 11, 2009
Nucl. Acids Res. 2010 38: 1664-1675; doi:10.1093/nar/gkp1104 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

RNA

Get checked abstract Ming-Yuan Chou and Kung-Yao Chang

An intermolecular RNA triplex provides insight into structural determinants for the pseudoknot stimulator of –1 ribosomal frameshifting
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: 1676-1685; doi:10.1093/nar/gkp1107 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract Cheryl Bolinger, Amit Sharma, Deepali Singh, Lianbo Yu, and Kathleen Boris-Lawrie

RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1686-1696; doi:10.1093/nar/gkp1075 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Tarita Biver, Alessia Boggioni, Begoña García, José M. Leal, Rebeca Ruiz, Fernando Secco, and Marcella Venturini

New aspects of the interaction of the antibiotic coralyne with RNA: coralyne induces triple helix formation in poly(rA)•poly(rU)
Nucleic Acids Research Advance Access published on December 14, 2009
Nucl. Acids Res. 2010 38: 1697-1710; doi:10.1093/nar/gkp1146 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Ivan Dotu, William A. Lorenz, Pascal Van Hentenryck, and Peter Clote

Computing folding pathways between RNA secondary structures
Nucleic Acids Research Advance Access published on December 30, 2009
Nucl. Acids Res. 2010 38: 1711-1722; doi:10.1093/nar/gkp1054 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Structural Biology

Get checked abstract Dimitra Serfiotis-Mitsa, Andrew P. Herbert, Gareth A. Roberts, Dinesh C. Soares, John H. White, Garry W. Blakely, Dusan Uhrín, and David T. F. Dryden

The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1723-1737; doi:10.1093/nar/gkp1144 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Hsing-Mao Chu, Tzu-Ping Ko, and Andrew H.-J. Wang

Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides
Nucleic Acids Research Advance Access published on December 10, 2009
Nucl. Acids Res. 2010 38: 1738-1748; doi:10.1093/nar/gkp1093 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Synthetic Biology and Chemistry

Get checked abstract Glenna E. Meister, Srinivasan Chandrasegaran, and Marc Ostermeier

Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells
Nucleic Acids Research Advance Access published on December 9, 2009
Nucl. Acids Res. 2010 38: 1749-1759; doi:10.1093/nar/gkp1126 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Kazumitsu Onizuka, Yosuke Taniguchi, and Shigeki Sasaki

A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA
Nucleic Acids Research Advance Access published on January 31, 2010
Nucl. Acids Res. 2010 38: 1760-1766; doi:10.1093/nar/gkp930 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Methods Online

Get checked abstract Alex E. Pozhitkov, Idrissa Boube, Marius H. Brouwer, and Peter A. Noble

Beyond Affymetrix arrays: expanding the set of known hybridization isotherms and observing pre-wash signal intensities
Nucleic Acids Research Advance Access published on December 6, 2009
Nucl. Acids Res. 2010 38: e28; doi:10.1093/nar/gkp1122 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Igor V. Kutyavin

New approach to real-time nucleic acids detection: folding polymerase chain reaction amplicons into a secondary structure to improve cleavage of Förster resonance energy transfer probes in 5'-nuclease assays
Nucleic Acids Research Advance Access published on December 7, 2009
Nucl. Acids Res. 2010 38: e29; doi:10.1093/nar/gkp1138 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract Renaud Geslain, Laia Cubells, Teresa Bori-Sanz, Roberto Álvarez-Medina, David Rossell, Elisa Martí, and Lluís Ribas de Pouplana

Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: e30; doi:10.1093/nar/gkp1083 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract Elodie Ayel and Christophe Escudé

In vitro selection of oligonucleotides that bind double-stranded DNA in the presence of triplex-stabilizing agents
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: e31; doi:10.1093/nar/gkp1139 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Get checked abstract K. Nehlsen, S. Herrmann, J. Zauers, H. Hauser, and D. Wirth

Toxin–antitoxin based transgene expression in mammalian cells
Nucleic Acids Research Advance Access published on December 8, 2009
Nucl. Acids Res. 2010 38: e32; doi:10.1093/nar/gkp1140 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data] [Supplementary Data]  

Get checked abstract Nobutaka Suzuki, Toshihide Itou, Yoshinori Hasegawa, Tsuneko Okazaki, and Masashi Ikeno

Cell to cell transfer of the chromatin-packaged human β-globin gene cluster
Nucleic Acids Research Advance Access published on December 10, 2009
Nucl. Acids Res. 2010 38: e33; doi:10.1093/nar/gkp1168 [Abstract] [FREE Full Text] [Print PDF][Screen PDF]  

Get checked abstract Lorena Pantano, Xavier Estivill, and Eulàlia Martí

SeqBuster, a bioinformatic tool for the processing and analysis of small RNAs datasets, reveals ubiquitous miRNA modifications in human embryonic cells
Nucleic Acids Research Advance Access published on December 11, 2009
Nucl. Acids Res. 2010 38: e34; doi:10.1093/nar/gkp1127 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] [Supplementary Data]  

Front-Matter/Back-Matter

Nucleic Acids Research: VOLUME 38 ISSUE 5 2010
Nucl. Acids Res. 2010 38: i; doi:10.1093/nar/gkq190 [Extract] [FREE Full Text] [Print PDF][Screen PDF] [Request Permissions]  

Nucleic Acids Research
Nucl. Acids Res. 2010 38: ii; doi:10.1093/nar/gkq189 [Extract] [FREE Full Text] [Print PDF][Screen PDF] [Request Permissions]  

Subscriptions
Nucl. Acids Res. 2010 38: iii; doi:10.1093/nar/gkq191 [Extract] [FREE Full Text] [Print PDF][Screen PDF] [Request Permissions]  

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